Oklahoma City made eight of its first 10 3-point attempts in the second half and never trailed after scoring the final five points before halftime.
Serge Ibaka chipped in 15 points and 10 rebounds and Kevin Martin had 16 points off the bench for the Thunder, who haven't lost consecutive home games since dropping two of the first three to start the 2010-11 season.
Nick Young led Philadelphia with 21 points, and Jrue Holiday had 15 points and nine assists. The Sixers fell to 2-5 on their eight-game road trip, which concludes Saturday night at San Antonio.
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